CHEMBL106247


SMILES Cc1cccc(C)c1C(=O)N1CCC(C)(N2CCC(Cc3ccc(Br)cc3)CC2)CC1
InChIKey ZVCMZXYHBQKEGX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 482.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCR5 CCR5 Mouse Chemokine A pKi 7.24 7.24 7.24 ChEMBL
CCR5 CCR5 Human Chemokine A pKi 7.18 7.21 7.24 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 5.88 5.88 5.88 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database