CHEMBL3326982


SMILES COc1ccccc1N1CCN(CCCCC(=O)NCc2ccccc2-c2ccccc2Cl)CC1
InChIKey JUVUVFRLXMQWRG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 10
Molecular weight (Da) 491.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 5.93 5.93 5.93 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 6.88 6.88 6.88 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.38 6.38 6.38 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.06 8.06 8.06 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.82 5.82 5.82 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.58 7.58 7.58 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.32 6.32 6.32 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.7 7.7 7.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database