CHEMBL3326993


SMILES COc1ccccc1N1CCN(CCCCCC(=O)NCc2ccccc2-c2ccccc2Cl)CC1
InChIKey IAKYDYYOYGXWAX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 11
Molecular weight (Da) 505.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 6.29 6.29 6.29 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 8.15 8.15 8.15 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.91 6.91 6.91 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.8 7.8 7.8 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.88 5.88 5.88 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.16 7.16 7.16 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.11 7.11 7.11 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.96 7.96 7.96 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database