CHEMBL333345


SMILES Cc1cc2c(cc1Cc1ccc(C(=O)NCc3cccc(CNc4ccnc(NC[C@H]5CCCO5)n4)c3)o1)C(C)(C)CCC2(C)C
InChIKey OOIJQVADMZQMAU-SSEXGKCCSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 11
Molecular weight (Da) 621.4

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GnRH1 GNRHR Rat Gonadotrophin-releasing hormone A pKi 8.33 8.33 8.33 ChEMBL
GnRH1 GNRHR Rat Gonadotrophin-releasing hormone A pKd 8.25 8.25 8.25 ChEMBL
GnRH1 GNRHR Human Gonadotrophin-releasing hormone A pKi 8.03 8.03 8.03 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database