CHEMBL333519


SMILES N[C@@]1(C(=O)O)CC[C@@H]2[C@H]1[C@@]2(F)C(=O)O
InChIKey GLDRBCJXSGSXEU-JKBXLQNXSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 2
Molecular weight (Da) 203.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Rat Metabotropic glutamate C pKi 7.38 7.38 7.38 ChEMBL
mGlu2 GRM2 Rat Metabotropic glutamate C pKi 7.65 7.65 7.65 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Rat Metabotropic glutamate C pEC50 7.09 7.09 7.09 ChEMBL
mGlu2 GRM2 Rat Metabotropic glutamate C pEC50 5.95 7.07 7.78 ChEMBL