CHEMBL334014


SMILES N[C@@]1(C(=O)O)[C@@H](F)C[C@H]2[C@H](C(=O)O)[C@H]21
InChIKey DIWVNJFXRKZAGI-FJNNMDBYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 2
Molecular weight (Da) 203.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Rat Metabotropic glutamate C pKi 7.18 7.18 7.18 ChEMBL
mGlu2 GRM2 Rat Metabotropic glutamate C pKi 7.32 7.32 7.32 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pEC50 7.12 7.12 7.12 ChEMBL
mGlu3 GRM3 Rat Metabotropic glutamate C pEC50 7.01 7.17 7.34 ChEMBL
mGlu2 GRM2 Rat Metabotropic glutamate C pEC50 5.58 6.78 7.53 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pEC50 6.82 6.82 6.82 ChEMBL