CHEMBL3355956


SMILES CCc1c(C2CCN(CCCSc3ccc(F)cc3)CC2)c2ccc(F)cc2n1-c1ccc(C(=O)O)cn1
InChIKey YUCBOQQXHCEAOT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 535.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCR3 CCR3 Rat Chemokine A pKi 5.96 5.96 5.96 ChEMBL
CCR3 CCR3 Mouse Chemokine A pKi 6.2 6.2 6.2 ChEMBL
CCR3 CCR3 Human Chemokine A pKi 7.8 7.8 7.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCR3 CCR3 Human Chemokine A pIC50 6.27 6.83 7.4 ChEMBL