CHEMBL361457


SMILES Cc1cc2c(CC(=O)O)cccc2n1C(=O)c1ccc(OCCc2ccccc2)cc1
InChIKey JLYOJYCKWIZTAQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 413.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
DP1 PD2R Mouse Prostanoid A pKi 8.74 8.74 8.74 ChEMBL
EP2 PE2R2 Mouse Prostanoid A pKi 5.89 5.89 5.89 ChEMBL
EP4 PE2R4 Mouse Prostanoid A pKi 5.72 5.72 5.72 ChEMBL
EP3 PE2R3 Mouse Prostanoid A pKi 5.66 5.66 5.66 ChEMBL
EP1 PE2R1 Mouse Prostanoid A pKi 6.4 6.4 6.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
DP1 PD2R Mouse Prostanoid A pIC50 6.92 6.92 6.92 ChEMBL