CHEMBL3616852


SMILES CC(C)c1nnc(S[C@@H]2C[C@@](N)(C(=O)O)[C@@H]3[C@@H](C(=O)O)[C@H]23)[nH]1
InChIKey INNYBEXRWKVEPM-VJVNAPCNSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 5
Molecular weight (Da) 326.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu2 GRM2 Human Metabotropic glutamate C pKi 6.58 6.58 6.58 ChEMBL
mGlu3 GRM3 Human Metabotropic glutamate C pKi 6.8 6.8 6.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu2 GRM2 Human Metabotropic glutamate C pEC50 7.06 7.42 7.78 ChEMBL
mGlu3 GRM3 Human Metabotropic glutamate C pEC50 6.55 6.55 6.55 ChEMBL
mGlu3 GRM3 Human Metabotropic glutamate C pIC50 6.07 6.07 6.07 ChEMBL