CHEMBL3616856


SMILES N[C@@]1(C(=O)O)C[C@H](Sc2nnc(C(F)(F)F)[nH]2)[C@H]2[C@H](C(=O)O)[C@H]21
InChIKey HHUBIRLCPJRLDB-CWOZVJDESA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 4
Molecular weight (Da) 352.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu2 GRM2 Human Metabotropic glutamate C pKi 8.07 8.07 8.07 ChEMBL
mGlu3 GRM3 Human Metabotropic glutamate C pKi 7.37 7.37 7.37 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu2 GRM2 Human Metabotropic glutamate C pEC50 8.11 8.65 9.19 ChEMBL
mGlu3 GRM3 Human Metabotropic glutamate C pIC50 6.21 6.21 6.21 ChEMBL
mGlu3 GRM3 Human Metabotropic glutamate C pEC50 7.52 7.52 7.52 ChEMBL