CHEMBL363730


SMILES CC1CN(/C(=N/c2ccc(C(=O)NCCc3ccc(Cl)cc3Cl)cc2)NC2CCCCC2)CC(C)N1
InChIKey QDDPPGFVMRPNTQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 6
Molecular weight (Da) 529.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC5 MC5R Human Melanocortin A pKi 7.96 7.96 7.96 ChEMBL
MC3 MC3R Human Melanocortin A pKi 5.41 5.41 5.41 ChEMBL
MC4 MC4R Human Melanocortin A pKi 6.23 6.23 6.23 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC5 MC5R Human Melanocortin A pIC50 7.1 7.1 7.1 ChEMBL
MC4 MC4R Human Melanocortin A pEC50 5.4 5.4 5.4 ChEMBL