CHEMBL363984


SMILES Cc1cc2c(CC(=O)O)cccc2n1C(=O)c1ccc(OCC2Cc3ccccc3O2)cc1
InChIKey PUNPVQHDYGWYHY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 441.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
DP1 PD2R Mouse Prostanoid A pKi 7.7 7.7 7.7 ChEMBL
EP1 PE2R1 Mouse Prostanoid A pKi 5.11 5.11 5.11 ChEMBL
EP3 PE2R3 Mouse Prostanoid A pKi 6.01 6.01 6.01 ChEMBL
DP1 PD2R Human Prostanoid A pKi 7.7 7.7 7.7 ChEMBL
EP2 PE2R2 Mouse Prostanoid A pKi 6.35 6.35 6.35 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
DP1 PD2R Human Prostanoid A pIC50 7.52 7.52 7.52 ChEMBL