CHEMBL3394830


SMILES CC1CCC(Oc2cccc3cnccc23)CN1C(=O)c1ccccc1-n1nccn1
InChIKey HMRXGDJBJTWHMJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 413.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKi 6.38 6.38 6.38 ChEMBL
OX2 OX2R Human Orexin A pKi 8.12 8.12 8.12 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database