CHEMBL3634006


SMILES CC(NC(=O)COc1cc(C(F)(F)F)c2c(-c3ccccc3)nn(C)c2n1)c1ccccc1
InChIKey OFEXDHUBLMOHCY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 454.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX2 OX2R Human Orexin A pKi 6.78 6.95 7.11 ChEMBL
OX2 OX2R Human Orexin A pKd 7.2 7.2 7.2 ChEMBL
OX1 OX1R Human Orexin A pKd 7.44 7.44 7.44 ChEMBL
OX1 OX1R Human Orexin A pKi 6.92 6.99 7.06 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database