CHEMBL3634018


SMILES C[C@H](NC(=O)COc1cc(C(F)(F)F)c2c(-c3ccccc3)nn(C)c2n1)c1ccccc1
InChIKey OFEXDHUBLMOHCY-HNNXBMFYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 454.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKd 7.19 7.19 7.19 ChEMBL
OX1 OX1R Human Orexin A pKi 6.76 6.76 6.76 ChEMBL
OX2 OX2R Human Orexin A pKd 6.92 6.92 6.92 ChEMBL
OX2 OX2R Human Orexin A pKi 6.97 6.97 6.97 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database