CHEMBL3403330


SMILES O=S(=O)(Nc1ccn(Cc2cccc3ccccc23)n1)c1ccc(Br)s1
InChIKey RPLQEGGEFLZVOJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 447.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 4.9 4.9 4.9 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 4.92 4.92 4.92 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 4.73 4.73 4.73 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.37 5.37 5.37 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database