CHEMBL340816


SMILES O=C(CCCN1C2CCC1CC(c1ccccc1)C2)c1ccc(F)cc1
InChIKey LECUUDCCVOYUHG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 351.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Human Histamine A pKi 6.01 6.01 6.01 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.75 6.75 6.75 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.97 5.97 5.97 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.97 6.97 6.97 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.38 6.38 6.38 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.91 6.91 6.91 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.91 6.91 6.91 PDSP Ki database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.38 6.38 6.38 PDSP Ki database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.97 6.97 6.97 PDSP Ki database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.97 5.97 5.97 PDSP Ki database
D4 DRD4 Human Dopamine A pKi 6.75 6.75 6.75 PDSP Ki database
H1 HRH1 Human Histamine A pKi 6.01 6.01 6.01 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database