CHEMBL3647963


SMILES O=C(O)c1nc2ccccc2n([C@@H]2C[C@@H]3CC[C@H](C2)N3C2CCCCCCCCCCC2)c1=O
InChIKey DNQQJKRDKSYDKP-JKHIJQBDSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 465.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 7.37 7.37 7.37 ChEMBL
δ OPRD Human Opioid A pKi 4.74 4.74 4.74 ChEMBL
κ OPRK Human Opioid A pKi 4.74 6.64 7.12 ChEMBL
μ OPRM Human Opioid A pKi 5.84 5.84 5.84 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database