CHEMBL364841


SMILES Cc1cc2c(CC(=O)O)cccc2n1C(=O)c1ccc(OC[C@@H]2CN(C)c3ccccc3O2)cc1
InChIKey XECAIYOLUPUKEJ-QFIPXVFZSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 470.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
FP PF2R Mouse Prostanoid A pKi 5.51 5.51 5.51 ChEMBL
DP1 PD2R Mouse Prostanoid A pKi 7.8 7.85 8.0 ChEMBL
EP1 PE2R1 Mouse Prostanoid A pKi 5.21 5.21 5.21 ChEMBL
EP2 PE2R2 Mouse Prostanoid A pKi 7.0 7.0 7.0 ChEMBL
EP3 PE2R3 Mouse Prostanoid A pKi 5.77 5.77 5.77 ChEMBL
IP PI2R Human Prostanoid A pKi 7.43 7.43 7.43 ChEMBL
DP1 PD2R Human Prostanoid A pKi 8.46 8.46 8.46 ChEMBL
TP TA2R Human Prostanoid A pKi 6.58 6.58 6.58 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
DP1 PD2R Mouse Prostanoid A pIC50 8.62 8.62 8.62 ChEMBL
DP1 PD2R Human Prostanoid A pIC50 7.24 8.08 8.92 ChEMBL