CHEMBL3422427


SMILES CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
InChIKey SQUAUCLQDKENKJ-HVRNLMOBSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 10
Rotatable bonds 18
Molecular weight (Da) 860.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC3 MC3R Mouse Melanocortin A pKd 5.4 5.4 5.4 ChEMBL
MC4 MC4R Mouse Melanocortin A pKd 7.8 7.8 7.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC5 MC5R Mouse Melanocortin A pEC50 5.55 5.55 5.55 ChEMBL
MC1 MSHR Mouse Melanocortin A pEC50 5.7 5.7 5.7 ChEMBL