ESATENOLOL


SMILES CC(C)NC[C@H](O)COc1ccc(CC(N)=O)cc1
InChIKey METKIMKYRPQLGS-LBPRGKRZSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 8
Molecular weight (Da) 266.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β1 ADRB1 Human Adrenoceptors A pKi 8.17 8.17 8.17 Drug Central
β2 ADRB2 Human Adrenoceptors A pKi 8.3 8.3 8.3 Drug Central
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.3 8.3 8.3 Drug Central
β2 ADRB2 Guinea pig Adrenoceptors A pKd 8.23 8.23 8.23 Drug Central
β1 B0FL73 Guinea pig Adrenoceptors A pKd 8.12 8.12 8.12 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M1 ACM1 Rat Acetylcholine (muscarinic) A Potency 4.95 5.82 7.1 ChEMBL
TSH TSHR Human Glycoprotein hormone A Potency 7.3 7.3 7.3 ChEMBL
A3 AA3R Human Adenosine A pIC50 8.06 8.06 8.06 Drug Central