CHEMBL347796


SMILES c1ccc(C(CCc2nc(CCNCCCCc3ccccn3)c[nH]2)c2ccccc2)cc1
InChIKey XPTQCQILQOIXEE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 13
Molecular weight (Da) 438.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Rat Histamine A pKd 8.21 8.21 8.21 ChEMBL
H1 HRH1 Guinea pig Histamine A pKd 8.79 8.79 8.79 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Rat Histamine A pEC50 6.62 6.62 6.62 ChEMBL
H1 HRH1 Guinea pig Histamine A pEC50 7.85 8.0 8.16 ChEMBL