UCSF924


SMILES Cc1ccc2nc(CNCCCOc3ccccc3)cc(O)c2c1
InChIKey RPHDOVLXDYWDGF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 322.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H2 HRH2 Human Histamine A pKi 5.72 5.72 5.72 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.31 8.76 9.7 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.63 6.63 6.63 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.65 6.65 6.65 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pEC50 8.38 8.38 8.38 ChEMBL