CHEMBL366042


SMILES CC(C)(N)C/N=C(\Nc1ccc(C(=O)NCCc2ccc(Cl)cc2Cl)cc1)NC1CCCCC1
InChIKey VOAHDPCQCTZCKL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 4
Rotatable bonds 8
Molecular weight (Da) 503.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC5 MC5R Human Melanocortin A pKi 8.28 8.28 8.28 ChEMBL
MC3 MC3R Human Melanocortin A pKi 5.62 5.62 5.62 ChEMBL
MC4 MC4R Human Melanocortin A pKi 5.89 5.89 5.89 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC5 MC5R Human Melanocortin A pIC50 6.28 6.28 6.28 ChEMBL
MC4 MC4R Human Melanocortin A pEC50 5.54 5.54 5.54 ChEMBL