CHEMBL352234


SMILES COc1cccc(N2CCN(C(=O)COc3ccc4[nH]cc(CCN)c4c3)CC2)c1
InChIKey JXZFKONVCRZNRZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 408.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 8.7 9.05 9.4 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.01 8.01 8.01 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pEC50 9.62 9.62 9.62 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pEC50 7.07 7.07 7.07 ChEMBL