CHEMBL35226


SMILES CCCN1CCC(COc2nc3ccccc3c3c2CCCN3)CC1
InChIKey UTMXFLLOSBJGIE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 339.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT4 5HT4R Guinea pig 5-Hydroxytryptamine A pKi 8.54 8.54 8.54 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT4 5HT4R Mouse 5-Hydroxytryptamine A pIC50 9.25 9.25 9.25 ChEMBL
V1B V1BR Rat Vasopressin and oxytocin A pIC50 5.5 5.5 5.5 ChEMBL
V2 V2R Pig Vasopressin and oxytocin A pIC50 4.96 4.96 4.96 ChEMBL
5-HT1A 5HT1A Mouse 5-Hydroxytryptamine A pIC50 5.04 5.04 5.04 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pIC50 6.7 6.7 6.7 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 5.47 5.47 5.47 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 5.3 5.3 5.3 ChEMBL
D2 DRD2 Human Dopamine A pIC50 5.47 5.47 5.47 ChEMBL