CHEMBL1188090


SMILES CCCN(CCc1ccccc1)CCc1cccc(O)c1
InChIKey QUZUPTMNMJTYGL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 283.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pKi 7.66 7.66 7.66 ChEMBL
κ OPRK Human Opioid A pKi 8.09 8.09 8.09 ChEMBL
μ OPRM Human Opioid A pKi 6.23 6.23 6.23 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.19 7.19 7.19 ChEMBL
δ OPRD Human Opioid A pKi 5.43 5.43 5.43 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pIC50 6.12 6.12 6.12 ChEMBL
D3 DRD3 Human Dopamine A pEC50 8.27 8.27 8.27 ChEMBL
κ OPRK Human Opioid A pEC50 7.31 7.31 7.31 ChEMBL
D2 DRD2 Human Dopamine A pEC50 7.41 7.41 7.41 ChEMBL
D1 DRD1 Rat Dopamine A pIC50 4.03 4.03 4.03 ChEMBL
κ OPRK Guinea pig Opioid A pIC50 7.24 7.24 7.24 ChEMBL