MSD-CYP11B2-Negative-control


SMILES FC(F)(F)c1ccc2c(c1)nc(-c1cccnc1)n2C1CC1
InChIKey RNBRMUYDOIRYOA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 303.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.51 5.51 5.51 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.97 5.97 5.97 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database