CHEMBL3665718


SMILES Cc1cc(-c2nn(C)c3nc(OCC(=O)NC(C)c4c(C)nn(C)c4C)cc(C)c23)c(C)o1
InChIKey LIKACLHWOBAKJP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 450.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKd 7.85 7.85 7.85 ChEMBL
OX2 OX2R Human Orexin A pKd 6.9 6.9 6.9 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database