CHEMBL3665723


SMILES COc1ccc([C@H](C)NC(=O)COc2cc(C(F)F)c3c(-c4cc(C)oc4C)nn(C)c3n2)cc1
InChIKey YIWTXIFCMFZIRO-AWEZNQCLSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 484.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKd 7.7 7.7 7.7 ChEMBL
OX2 OX2R Human Orexin A pKd 7.19 7.19 7.19 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database