CHEMBL3665734


SMILES Cc1ccc2c(n1)CC[C@@H]2NC(=O)COc1cc(C(F)(F)F)c2c(-c3cc(C)oc3C)nn(C)c2n1
InChIKey OEOHGCWORFHBJS-IBGZPJMESA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 499.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKd 7.47 7.47 7.47 ChEMBL
OX2 OX2R Human Orexin A pKd 7.05 7.05 7.05 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database