CHEMBL3597591


SMILES O=[N+]([O-])c1cccnc1N1CCN(CC#Cc2ccccc2)CC1
InChIKey LJYNSIUTUVNOQT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 322.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 6.93 6.93 6.93 ChEMBL
mGlu5 GRM5 Human Metabotropic glutamate C pKi 7.22 7.22 7.22 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database