CHEMBL3616853


SMILES N[C@@]1(C(=O)O)C[C@@H](Sc2c[nH]nn2)[C@H]2[C@H](C(=O)O)[C@H]21
InChIKey RXZDXHKRDHZRKP-NVPUNQSHSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 4
Molecular weight (Da) 284.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pKi 6.59 6.59 6.59 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pKi 6.85 6.85 6.85 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pIC50 5.26 5.44 5.62 ChEMBL
mGlu3 GRM3 Human Metabotropic glutamate C pEC50 6.63 6.63 6.63 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pEC50 7.34 7.62 7.91 ChEMBL