CHEMBL3646196


SMILES COc1ccnc(N2CC3CN(C(=O)c4ccccc4-c4cccs4)CC3C2)n1
InChIKey PFOXKHAUTFFHKO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 406.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX2 OX2R Human Orexin A pKi 7.44 7.44 7.44 ChEMBL
OX1 OX1R Human Orexin A pKi 6.14 6.14 6.14 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database