CHEMBL3648460


SMILES COC(=O)c1c(Cl)cccc1-c1ccc2c(c1)CCCC2NC(=O)C1(NC(=O)C(F)(F)F)CC1
InChIKey RIOBXZSQDXGNJE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 494.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
B1 BKRB1 Human Bradykinin A pKi 6.28 6.28 6.28 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
B1 BKRB1 Human Bradykinin A pIC50 6.93 6.93 6.93 ChEMBL