CHEMBL3648461


SMILES Cc1nc(-c2c(F)cc(Cl)cc2-c2ccc3c(c2)CCCC3NC(=O)C2(NC(=O)C(F)(F)F)CC2)no1
InChIKey IAWVOODBIZSXKE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 536.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
B1 BKRB1 Human Bradykinin A pKi 7.38 7.38 7.38 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
B1 BKRB1 Human Bradykinin A pIC50 8.4 8.4 8.4 ChEMBL