CHEMBL3649086


SMILES COc1ccc(N2CC3CN(C(=O)c4ccccc4-c4cccs4)CC3C2)nc1
InChIKey HMKUPSOTYRPXCT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 405.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKi 5.05 5.05 5.05 ChEMBL
OX2 OX2R Human Orexin A pKi 6.04 6.04 6.04 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database