CHEMBL370378


SMILES Cn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(Br)cc4)cc3)cc2n(C)c1=O
InChIKey AZGRESCKAVVMKU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 482.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
A2A AA2AR Rat Adenosine A pKd 6.9 6.9 6.9 ChEMBL
A2B AA2BR Human Adenosine A pKi 8.58 8.58 8.58 ChEMBL
A2B AA2BR Human Adenosine A pKd 8.06 8.29 8.53 ChEMBL
A2A AA2AR Human Adenosine A pKd 5.99 5.99 5.99 ChEMBL
A2A AA2AR Human Adenosine A pKi 5.91 5.91 5.91 ChEMBL
A1 AA1R Human Adenosine A pKi 7.74 7.74 7.74 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database