CHEMBL3659218


SMILES COc1c(F)cccc1C(=O)N1C2CCC1C(COc1ccc(Br)cn1)C2
InChIKey HMNUCRNMECNDCA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 434.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Rat Orexin A pKi 6.34 6.34 6.34 ChEMBL
OX2 OX2R Human Orexin A pKi 5.36 5.36 5.36 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database