CHEMBL3663412


SMILES COc1c(F)cccc1C(=O)N1C2CCC1C(COc1ccc(F)cn1)C2
InChIKey KLDKRPGZCSJCEY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 374.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Rat Orexin A pKi 5.9 6.13 6.36 ChEMBL
OX2 OX2R Human Orexin A pKi 5.52 5.59 5.66 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database