CHEMBL3665678


SMILES C[C@H](NC(=O)COc1cc(C(F)(F)F)c2c(-c3ccc(F)cc3)nn(C)c2n1)c1ccccc1
InChIKey PYLDHNBUFJCMQT-AWEZNQCLSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 472.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKd 6.88 6.88 6.88 ChEMBL
OX2 OX2R Human Orexin A pKd 6.56 6.56 6.56 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database