CHEMBL3669438


SMILES O=C1N(Cc2ccc3c(c2)OCO3)CCCC12CCN(c1cnc3ccccc3n1)CC2
InChIKey ONVQIMRWQOAOKB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 430.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKd 5.63 5.63 5.63 ChEMBL
OX1 OX1R Human Orexin A pKi 5.91 5.91 5.91 ChEMBL
OX2 OX2R Human Orexin A pKi 6.4 6.4 6.4 ChEMBL
OX2 OX2R Human Orexin A pKd 6.23 6.23 6.23 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database