CHEMBL3669440


SMILES O=C1N(Cc2ccccc2)CCCC12CCN(c1nc3ccccc3[nH]1)CC2
InChIKey JGQMNLQDUUXCLD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 374.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKd 5.47 5.47 5.47 ChEMBL
OX2 OX2R Human Orexin A pKi 5.97 5.97 5.97 ChEMBL
OX2 OX2R Human Orexin A pKd 6.36 6.36 6.36 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database