CHEMBL3669452


SMILES O=C1N(Cc2cccc(-c3ccccc3)c2)CCCC12CCN(c1cnc3ccccc3n1)CC2
InChIKey DHBHYLLJTLRILL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 462.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKd 5.88 5.88 5.88 ChEMBL
OX1 OX1R Human Orexin A pKi 6.29 6.29 6.29 ChEMBL
OX2 OX2R Human Orexin A pKd 7.23 7.23 7.23 ChEMBL
OX2 OX2R Human Orexin A pKi 7.29 7.29 7.29 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database