CHEMBL3669453


SMILES O=C1N(Cc2ccccc2C(F)(F)F)CCCC12CCN(c1cnc3ccccc3n1)CC2
InChIKey LAZFQQSOMFUUKF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 454.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKd 5.35 5.35 5.35 ChEMBL
OX1 OX1R Human Orexin A pKi 5.56 5.56 5.56 ChEMBL
OX2 OX2R Human Orexin A pKi 6.55 6.55 6.55 ChEMBL
OX2 OX2R Human Orexin A pKd 5.96 5.96 5.96 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database