CHEMBL3669467


SMILES Cn1ccc2c(CN3C(=O)CCCC34CCN(c3cnc5ccccc5n3)CC4)cccc21
InChIKey ITYCFGYDQTYTHU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 439.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKi 7.19 7.19 7.19 ChEMBL
OX1 OX1R Human Orexin A pKd 7.25 7.25 7.25 ChEMBL
OX2 OX2R Human Orexin A pKi 7.32 7.32 7.32 ChEMBL
OX2 OX2R Human Orexin A pKd 6.9 6.9 6.9 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database