CHEMBL3669470


SMILES O=C1N(Cc2ccccc2-n2nccn2)CCCC12CCN(c1cnc3ccccc3n1)CC2
InChIKey UQDZEOCEKHULPR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 453.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKd 5.49 5.49 5.49 ChEMBL
OX1 OX1R Human Orexin A pKi 5.67 5.67 5.67 ChEMBL
OX2 OX2R Human Orexin A pKi 7.41 7.41 7.41 ChEMBL
OX2 OX2R Human Orexin A pKd 6.94 6.94 6.94 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database