CHEMBL3669476


SMILES O=C1N(Cc2c[nH]c3ncccc23)CCCC12CCN(c1cnc3ccccc3n1)CC2
InChIKey PLYROBNEDAWALN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 426.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKi 5.99 5.99 5.99 ChEMBL
OX1 OX1R Human Orexin A pKd 6.02 6.02 6.02 ChEMBL
OX2 OX2R Human Orexin A pKi 7.04 7.04 7.04 ChEMBL
OX2 OX2R Human Orexin A pKd 6.8 6.8 6.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database