CHEMBL3669478


SMILES O=C1N(Cc2cccc(-n3cccn3)c2)CCCC12CCN(c1cnc3ccccc3n1)CC2
InChIKey MFNJDWIRSNXGEX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 452.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKd 6.14 6.14 6.14 ChEMBL
OX1 OX1R Human Orexin A pKi 6.41 6.41 6.41 ChEMBL
OX2 OX2R Human Orexin A pKi 7.31 7.31 7.31 ChEMBL
OX2 OX2R Human Orexin A pKd 6.72 6.72 6.72 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database