CHEMBL3669483


SMILES O=C1N(Cc2cccc(-c3cnccn3)c2)CCCC12CCN(c1cnc3ccccc3n1)CC2
InChIKey MANWMDXZWSBIHD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 464.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKd 5.73 5.73 5.73 ChEMBL
OX1 OX1R Human Orexin A pKi 6.45 6.45 6.45 ChEMBL
OX2 OX2R Human Orexin A pKi 7.64 7.64 7.64 ChEMBL
OX2 OX2R Human Orexin A pKd 6.21 6.21 6.21 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database